glp-1 discovery JCI AI-Driven Design of GLP-1R PAMs

Clinical studies Compared with the considerable amount of pre-clinical and mechanistic research reported above, we identified few clinical studies of GLP-1RAs for substance-use disorders (Table 2): three for alcohol 111,112,113 , one for cannabis 114 , two for cocaine 115,116 and two for nicotine 117,118 , while no article about opiates or amphetamines was retrieved

Cardiovascular Risk Reduction# Recommendation : Semaglutide Reason : SELECT demonstrated 20% MACE reduction with semaglutide 2.4 mg in 17,604 patients

Copper-instigated modulatory cell mortality mechanisms and progress in kidney diseases

Wirksam erhhen lsst sich der Glutathion-Spiegel allein durch eine Eumetabol-Therapie, da nur bei dieser Glutathion-Therapie das GSH wirksam gegen Oxidierung geschtzt ist