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With only one approved treatment available for MASH, new options are urgently needed
When to seek urgent medical help: Whilst most gastrointestinal side effects are mild and self-limiting, participants and clinicians should be alert to the following red-flag symptoms, which require prompt medical assessment: Severe or persistent abdominal pain (which may indicate pancreatitis or gallbladder disease) Repeated vomiting or an inability to keep fluids down Signs of dehydration (such as dizziness, dark urine, or reduced urine output) Yellowing of the skin or eyes (jaundice) Anyone who suspects they have experienced a side effect from a medicine including medicines received as part of a clinical trial should report it via the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk)
Better health is worth the effort.
I recommend against this because changing reflects perception more than true effectiveness and tirzepatide does work better than semaglutide for most patients. What role do genetics play in how well GLP-1 drugs work
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