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The reaction is particular for thiol groups and characterized by fast kinetics, making it suitable for measuring thiol concentrations in various biological systems
The topical concentration determines how much peptide reaches dermal tissue per application
While it comes with potential side effects like dry skin, sun sensitivity, and the need for strict pregnancy prevention, its ability to eliminate deep, cystic acne and prevent scarring makes it worth it for many people
Karandikar A, Thangarajan S (2017) Protective activity of esculetin against 3-nitropropionic acid induced neurotoxicity via scavenging reactive oxygen species in male Wistar rats
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