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Our group has recently invented a molecular combination (cARLA) synergistically targeting signaling pathways related to BBB maturation that elevated the barrier tightness and other BBB-specific properties in several BBB culture models including human stem cell-based ones [40]
Rodrguez-Carrio J, Salazar N, Margolles A, Gonzlez S, Gueimonde M, de Los Reyes-Gaviln CG, et al
A key focus is placed on the dysregulation of the kynurenine pathway of tryptophan metabolism, which mechanistically links immune activation to neurotransmitter imbalances
BPC-157 is studied for gut healing and tendon and ligament repair
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