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Discussion Genetic fusion of protein-based drugs to the N-terminal or C-terminal end of albumin, or both, offers a feasible and attractive approach to enhance the PK properties and therapeutic efficacy of short-lived biologics 6,7

doi:10.1111/j.1365-3164.2007.00647.x

J Clin Endocrinol Metab 89:30553061 Muskiet MH, Tonneijck L, Smits MM, Kramer MH, Diamant M, Joles JA, van Raalte DH (2016) Acute renal haemodynamic effects of glucagon-like peptide-1 receptor agonist exenatide in healthy overweight men

From 1924 several researchers began to investigate the effect of injected and orally administered duodenal (secretin) extracts on fasting blood glucose levels and hyperglycemia (high blood sugar) in normal and diabetic animals and humans