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Production of panic-like symptoms by lactate is associated with increased neural firing and oxidation of brain redox in the rat hippocampus
A 2024 review surveyed neurotransmitter-system interactions in this body of work (PMID 38675421), suggesting the compound's effects on central nervous system tissue may share mechanisms with its peripheral activity
People with this chronic, progressive neurological disorder have high levels of oxidative stress and premature cellular die off in a part of the brain called the substantia nigra
To our knowledge, tissue NFT concentrations have not yet been determined in specific human organs
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