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The decreased expression of ATGL inhibits fatty acid mobilization of intracellular lipid droplets and promotes lipid droplet's aggregation, leading to renal tubular epithelial cell injury and renal fibrosis, and ultimately promotes the transformation of AKI to CKD[27]

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Meanwhile, weight continued to decline ( 3.4 kg total), and HbA1c had improved to 7.2%, confirming that semaglutide was maintaining its glycaemic effect throughout

These neurons migrate over long distances to enter cortical and subcortical regions, playing crucial roles in maintaining the brains excitation/inhibition balance and regulating synaptic plasticity