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A notable proportion of participants in the higher-dose groups achieved HbA1c levels below 48 mmol/mol (6.5%) the diagnostic threshold for type 2 diabetes in the UK and some reached levels at or below 42 mmol/mol (6.0%), which falls within the range of non-diabetic hyperglycaemia as defined by UK and WHO criteria

These findings highlight the potential pathological roles of NM accumulation in PD, suggesting therapeutic potentials of inhibiting time-dependent NM accumulation for PD

2011 Sep;94(3):938-44