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Because urate reabsorption has a greater transport capacity compared to urate secretion mechanisms, the net effect of high dose aspirin is uricosuric, with more urate being eliminated in the urine (Yu & Gutman, 1959)

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In the meantime, the regulator has agreed to not take action against compounders of tirzepatide until December 19, unless the agency makes an earlier decision on remand, according to a Leerink investor note issued last month