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(54) found that administering GIPR antagonist to healthy humans reduced postprandial insulin secretion and increased glucose excursions more than administering GLP-1R antagonist (GLP-1RA), indicating that endogenous GIP may play a more significant role in stimulating insulin secretion and reducing postprandial plasma glucose excursions compared to endogenous GLP-1

She still looks forward to coffee every day and has occasional cravings, but overall thinks she gets less pleasure from food than she used to

GLP-1 receptor agonists can be a game changer for weight loss

For example, rapid weight loss can temporarily affect hormones or cause hair shedding