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In: Kreutzer JS, DeLuca J, Caplan B, editors
Presented for research literature review only Forastieri H et al
The authors concluded: Further research is needed to determine if there is a true cause and effect relationship in the association identified in this investigation and to understand the trade-offs between the benefits and risks of GLP-1 RAs. Also in June, the European Medicines Agency safety committee warned that semaglutide (active substance in Ozempic, Rybelsus and Wegovy) may cause the NAION optic neuropathy described earlier in this article
By starting with smaller, more frequent doses and titrating up very gradually (e.g., monthly adjustments instead of weekly), the body has more time to adapt, leading to fewer and less severe side effects
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