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Seven additional phase 3 trials for retatrutide are expected to wrap up in 2026
Adding GIP enhances fat metabolism and improves insulin sensitivity, which is why tirzepatide outperforms semaglutide on weight loss
For MIA mice, a continuous ICV infusion of 2.5 g per day was administered over a seven-day period
Combined with the additional appetite-driven reduction from tirzepatide itself, total weight loss often exceeds this baseline rate, particularly in the early months of treatment
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