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Information sources and search The literature was explored using the MEDLINE (via PubMed) and Web of Science databases, including all articles published from the inception up February 2020
At the ingredient level, berberine has been studied for its potential effects on blood sugar regulation, lipid metabolism, and cellular energy pathways
Tirzepatide is a dual-action peptide that stimulates both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors, which may explain why some patients experience faster weight loss with tirzepatide compared to semaglutide alone
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