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Due to both the high abundance of GSH and the millimolar K d value, we observed F 405 /F 488 changes only when RT reacted with GSH but not other thiols, reactive oxygen or nitrogen species (ROS/RNS) at their corresponding physiological concentrations (Fig
293 Michalsen, A
At the end of treatment, the cell culture supernatants of each group were collected
While the full picture is still emerging, the breadth of these effects underscores why expectations for this drug class have soared
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