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Administration of lipoic acid (200 to 1,800 mg/day for 2 weeks to 1 year), alone or together with other nutrients, was found to lower fasting blood glucose and insulin concentrations, insulin resistance, and blood HbA1c concentration a marker of glycemic control over the past few months (60)

Glutaryl-CoA dehydrogenase (GCDH) deficiency is an inborn error of lysine and tryptophan metabolism that results in increased formation and excretion of glutaric acid (GA), 3-hydroxyglutaric acid (3-OH-GA), glutaconic acid and glutarylcarnitine [82]

doi: 10.1016/j.phymed.2025.156843 118 WuYZengMJiaoXMaXWangHChenYet al

The components are sold in the United States as research chemicals labeled for laboratory use only, not as approved drugs or supplements