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The researchers noted that the true prevalence is likely higher, because adverse event reporting for sexual side effects is notoriously underreported
Besides, by upregulating the cytochrome c oxidase 2 (SCO2) (167), TP53 initiates several transcriptional programs to promote the expression of genes related to mitochondrial biogenesis (168), such as apoptosis-inducing factor (AIF) (169, 170) and ferredoxin reductase (FDXR) (171)
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