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Over 250 pounds (113kg+): Maximum standard dosing of 500mcg applies, though some individuals may benefit from extending cycle length rather than increasing dose
Retatrutide works through incretin hormone receptors in the gut, pancreas, hypothalamus, and peripheral tissue
Timelines vary by tissue: gut symptoms often improve in 2 to 4 weeks, while tendon and ligament changes typically take 3 to 4 weeks to begin and longer to consolidate
Often sourced from unregulated labs overseas
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