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Stock solutions of 1 mg/mL are easily prepared without co-solvents

This metabolic dysregulation reduces mitochondrial energy production efficiency, adversely affecting cardiac contraction and relaxation functions (87)

Chronic pain: an update on burden, best practices, and new advances

Among them, the glutamate produced by the decomposition of glutamine via GLS not only provides the raw material for the synthesis of GSH but is also further metabolized into -ketoglutarate (-KG) in the mitochondria under the action of glutamate dehydrogenase (GLUD1) or transaminases and then enters the tricarboxylic acid cycle to produce ATP [29]