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For PDE10A, Compound 86 , JY4 (co-crystallized ligand), and TAK-063 (standard), all occupied the P-clamp, interacting with I692, F696, and F729
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People who use GLP-1s require high-protein meals, smaller and healthier snacks (think nuts, fruit, yogurt), nutrient-dense foods, and eat smaller meals at one sitting
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