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Once-weekly cagrilintide-semaglutide (at a dose of 2.4 mg each) resulted in a significantly lower body weight than placebo in adults with obesity and type 2
Limitations of current evidence include small sample sizes, short study durations, heterogeneous patient populations, and varying dosing regimens
These proteases exist as inactive zymogens and require proteolytic cleavage to become enzymatically active
Asensio-Lpez MC, Lax A, Pascual-Figal DA, Valds M, Snchez-Ms J
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