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To better visualize the changes between IC-B and PEC cells in ABMR compared with normal tissue, we assessed the following pathways related to glutathione metabolism, and vitamin A and biosynthetic machinery, based on cells expressing genes related to each significantly altered pathway, alongside average expression ( Supplementary Figures 4C, D )
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Thus, both CI and CII exhibited a significant lower activity, which was confirmed by a lower state apparent upon Gclc ablation (Supplementary Fig
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