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The International Menopause Society reports that for up to 25% of women, they can significantly lower quality of life due to physical discomfort, social embarrassment, sleep disruption, mood changes, and associated stress [7]

Furthermore, transcriptome map analyses were performed using Transcriptome Mapper (TRAM) software to investigate whether a difference in gene expression is detectable between subjects with T21 and euploid control group in tissues and cells involved in the immune response such as lymphoblastoid cells, thymus and white blood cells

doi: 10.1002/edm2.402

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