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Based on animal studies, ipamorelin actually increases the total body fat percentage of non-GH-deficient rodents [9]

Clinicians often integrate the product with calorie-restricted diets, resistance training, and behavior-change counseling to potentially maximize adipose mass reduction while preserving lean tissue, though evidence remains largely extrapolated from the individual components pharmacology and not from randomized controlled trials of the exact compounded combination

Only some carry FDA approval, and where they do, that approval is usually for a specific condition rather than for muscle building