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A 5 mg vial reconstituted with 2 mL gives 2,500 mcg/mL, so 200 mcg is 8 units and 300 mcg is 12 units per injection
The LEADER trial demonstrated that liraglutide significantly reduced the risk of cardiovascular death, nonfatal myocardial infarction, and nonfatal stroke
GLP-1 meds slow digestion
This endotype perspective is critical for GLP-1RA use: if an individuals primary driver is IR and a lipotoxic background, the posterior probability of response to GLP-1RAs is theoretically higher
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