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Quality assessment Potential risks of bias were evaluated for all included trials, using a tool for randomised trials (RoB 2) developed for this purpose.13 This tool assesses bias in five different domains: bias arising from the randomisation, bias due to deviations from the intended intervention, bias due to missing outcome data, bias in the measurement of the outcome and bias in the selection of the reported result
Among the other markers of atherosclerosis, BNP, which is secreted mainly by the ventricular myocardium 53,54,55 , has been found to decrease significantly by the GLP-1-based therapies but MCP-1, which is secreted by the peripheral blood mononuclear cells 56 , has been found un-affected by the GLP-1-based therapies, in the present study
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