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Some patients benefit more from semaglutide alone, while others see better results with tirzepatide (a dual GLP-1/GIP receptor agonist) or combination protocols like GLP-Squared

For weight management, NICE technology appraisals TA875 (semaglutide/Wegovy) and TA664 (liraglutide/Saxenda) recommend these medications only within specialist weight management services for adults with a BMI 35 kg/m (or 32.5 kg/m in certain ethnic groups) with weight-related comorbidities, and under specific time-limited conditions

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Skipping meals entirely is not a goal of tirzepatide therapy, even though reduced appetite might make that tempting