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The screens 25 top drug hits (Table S.4) were purchased from Selleck Chemicals for dose-response studies and prepared and stored per manufacturers instructions
Consistent with these biological roles, cytokine analysis revealed that EGCG-Zn significantly downregulated the pro-inflammatory cytokines IL-6 and TNF- while upregulating the anti-inflammatory cytokine IL-10 (Fig
In accordance with previous studies 28,29 , we administered a ferroptosis inducer, erastin, to HT1080 cell culture and observed decrease in GSH levels by flow cytometry of RT signals (Fig
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