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Configuring the device to output more or less force for different viscosity formulations or different dose volumes does not require any change to the device mechanism or components. The results for the spring-powered autoinjector show a peak force of 466 N, with a 115 N mean delivery force
Severe oxidant stress induced by excessive ROS has been shown to trigger cell apoptosis associated with damaged DNA, oxidation of polyunsaturated fatty acids and amino acids, as well as mitochondrial dysfunction (73)
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