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PARAMETER SAG REDUCED GSH Molecular Structure Acetylated modification (Thiol group protected) Free Thiol (-SH), unmodified Aqueous Stability Significantly higher
weight loss at target dose (trial data) ~21% (SURMOUNT) CV risk reduction labelled Under study Format Prefilled KwikPen + single-dose autoinjector India price (May 2026) 14,00027,500/month DCGI-approved Yes (March 2025) Generic competition in India No no Indian biosimilar yet Weight-loss percentages are trial averages at target dose individual response varies
Coffee has also been shown to reduce absorption and should be avoided for at least 30 minutes after taking levothyroxine
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