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12 With obesity progression, adipose tissue becomes inflamed and fibrotic, worsening the dysfunction and decreasing the WATs metabolic flexibility, leading to the development of metabolic abnormalities, such as dyslipidemia and IR

Women under 140 pounds typically respond well to 0.5mg daily, while those over 160 pounds may benefit from the full 1mg dose

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Athletic animals which exercise regularly and strenuously have B-Group vitamin requirements far in excess of their less athletic counterparts