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Databases searched (and their content coverage dates) were Ovid MEDLINE(R) (1946+ including epub ahead of print, in-process, and other nonindexed citations), Ovid Embase (1974+), Ovid APA PsycInfo (1967+), Ovid Cochrane Central Register of Controlled Trials (1991+), Ovid Cochrane Database of Systematic Reviews (2005+), Web of Science Core Collection via Clarivate Analytics (1975+), and Scopus via Elsevier (1974+)
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Past and future medical bills: This includes hospital stays, emergency room visits, specialist consultations (like gastroenterologists), diagnostic tests (like endoscopies), and prescription medications
34 The findings on gut microbiota and TS are largely consistent in highlighting the role of dysbiosis, gut-brain axis dysfunction, and neuroinflammation in the pathophysiology of TS
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