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Cysteine supply and GCL activity are important controls on this pathway
Side effects include: Gastrointestinal symptoms such as nausea, vomiting, constipation, and diarrhea Loss of lean body mass, with slides indicating that a substantial portion of weight loss may come from muscle Mood-related changes, including depression, anxiety, and suicidal behavior Increased risk of gallstones and hypoglycemia These effects may be especially concerning in patients with eating disorders, where nutritional status and medical stability are already compromised
Most adverse events were self-limited and gastrointestinal in nature [113]
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