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Neelakantan and colleagues (Biochem Pharmacol, 2017) then took the pharmacological step, reporting that selective, membrane-permeable small-molecule NNMT inhibitors reversed high-fat-diet-induced obesity in mice this is the study most directly relevant to the 5-Amino-1MQ class, because it moves from the target matters to a drug against the target does something in a live animal. And again, it is a mouse study
This is really helpful for people suffering from gut issues where the absorption of oral supplements may not be 100%
If my doctor stopped my injections and told me to take oral tablets I would simply carry on self-injecting and I suspect a great many other patients would do so too
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