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The symptoms of carpal tunnel syndrome include numbness, tingling, as well as pain in the thumb and the first three fingers of the hand, pain and burning which travels up the arm, wrist pain at night which interferes with sleep, as well as weakness in the mules of the hand

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Histological assays showed a lack of severe immune-cell infiltration in the liver of hepsin / mice compared to wild-type mice within 6 h post-APAP exposure, suggesting the need for further investigation of inflammation in hepsin-mediated APAP intoxication

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