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Here are some reasons for why you wouldnt to switch - The SURMOUNT-5 trial, the first head-to-head comparison of the two medications, published in the New England Journal of Medicine in May 2025, found that tirzepatide (Mounjaro 15mg) produced 20.2% average weight loss at 72 weeks, compared to 13.7% for semaglutide (Wegovy 2.4mg)
10.1016/j.ygcen.2017.08.008 76
No, you should still start at 2.5 mg even with previous GLP-1 medication experience
However, affinity chromatography with its versatile types is the only technique for highly purified and selective protein yield
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