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doi: 10.1038/s41574-019-0176-8 9 MaCAvenellABollandMHudsonJStewartFRobertsonCet al
the proposed relationship is cofactor supply
Clinical trials report nausea, vomiting, and abdominal pain in 2040% of patients, with cramping typically emerging during dose escalation phases
This inhibition was evidenced by Oil Red O and AdipoRed staining, and by the downregulation of key adipogenic markers, including peroxisome proliferator-activated receptor gamma ( PPAR ), lipoprotein lipase ( LPL ), fatty acid-binding protein 4 ( FABP4 ), and CCAAT/enhancer-binding protein alpha ( C/EBP ) [12, 13, 22, 23]
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