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Given the limited regenerative capacity of neurons, sustained disruption of proteostasis progressively overwhelms cellular quality control systems, leading to synaptic dysfunction, neurodegeneration and irreversible cognitive or motor decline
The reported values for different rows in this table were obtained under different conditions and should not be treated as a single ranking
doi: 10.18632/oncotarget.6907 251 HansenALBuchanGJRhlMMukaiKSalvatoreSROgawaEet al
Carcinogenesis 2007
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