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According to the results, the elimination half-life (t 1/2 ) of the prototype BPC157 was less than 30 min, and BPC157 showed linear pharmacokinetic characteristics in rats and beagles at all experimental doses
Dopamine is also a potent suppressor of ferroptosis, and thus, its reduced levels in PD may increase cellular susceptibility to ferroptosis
Preclinical studies have shown promising results: Specific strains such as Bifidobacterium breve and Lactobacillus plantarum reduce microglial activation, increase anti-inflammatory cytokines like IL-10, promote neurogenesis, and enhance cognitive performance in rodent models of AD [624, 625]
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