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Diabetic patients express SGLT2 receptors more frequently than non-diabetic ones, so glycosuria occurs when glycaemic values reach more than 220 mg/dl (12)
But if they occur soon after starting a GLP-1 RA especially alongside vomiting, diarrhea, or poor oral intake electrolyte imbalance should be on the list of possibilities
Sodium Glucose Cotransporter-2 Inhibitors are Not Associated with Amputation After Lower Extremity Revascularization in Patients with Diabetes, Annals of Vascular Surgery, 130 , (415-424), (2026)
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