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4 In another study evaluating topical glutathiones role on UV-induced erythema, Grandi et al 9 found that subjects pre-treated with S-acyl glutathione 2% cream, a linoleic acid pre-conjugate, had a significantly lower minimal erythema dose compared to placebo, indicating UV protective properties ( p =0.0003)

Furthermore, APP/PS1 mice exhibit significant hyperactivity in the dorsal raphe nucleus during reward-seeking and motivational actions (Sakurai et al., 2020), indicating complex interactions between A pathology and neural circuitry affecting behavior

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