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doi: 10.4168/aair.2023.15.2.262 80
It has been shown to enhance sperm motility, quality, and count
By regulating glutathione S-transferase (GST) and intracellular glutathione (GSH) levels, Nrf2 controls the level of ROS in the cell (Kolls, 2006
That comes from a different trial: the Phase 1 single-dose study in lean participants, where -hydroxybutyrate started below the assays detection floor and reached 708 mol/L at 4.5 mg by day 8 a large, dose-ordered rise in a lean cohort. The MASLD substudy, by contrast, found ketones moving only at 4 mg and above in a group with insulin resistance damping the readout
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