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Interestingly, strains from these genera often converge at the functional level in terms of production of short-chain fatty acids (SCFAs), such as propionate, acetate and butyrate that may exert anti-inflammatory effects [184]

Osteoarthritis usually develops from cartilage wear and joint degeneration over time, while rheumatoid arthritis is an autoimmune condition that causes inflammation inside the joints

This work lays the foundation for the development of potential therapeutics for the treatment of tumors that are highly dependent upon metabolic pathways involving GOT1 for the maintenance of redox homeostasis and sustained proliferation (e.g., PDAC)