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Focus on fiber-rich, complex carbs like oats, quinoa, sweet potatoes, brown rice, and beans

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For the earlier window mild cognitive impairment (MCI) and brain aging where synaptic loss is the dominant driver of symptoms and where the 2026 NICE rejection of lecanemab and donanemab has left a substantial UK treatment gap, the synaptic-rationale conversation continues even after the fosgonimeton failure

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The MHRA and EMA continuously monitor the safety of these medications, and patients are encouraged to report suspected side effects via the MHRA Yellow Card scheme

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Administered as a once-weekly subcutaneous injection, Zepbound is available in doses from 2.5 mg to 15 mg

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