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A deeper understanding of the conformational possibilities available to GPCRs bound to flexible agonists, and of relationships among conformational states and signal transduction, will enhance prospects for elucidating signal-propagating mechanisms at the molecular level and optimizing therapeutic performance
History & Research Background GHK was originally identified in human plasma and later studied in relation to age-associated changes, tissue-remodeling models, copper coordination, extracellular-matrix biology, and gene-expression patterns
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