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This dual mechanism is thought to be more effective than medications that target only one of these pathways
It depends on your goals
The mechanistic plausibility is strong (NNMT inhibition increases NAD+ without the gastrointestinal side effects of high-dose nicotinamide), and the short-term tolerability profile is excellent, but we mean this sincerely: if you're using this compound for durations beyond what the published trials covered, you are operating in uncharted territory
Additionally, B12 injections may support cognitive function, boost energy levels, and improve mood
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