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Retatrutide, a GIP, GLP-1 and glucagon receptor agonist, for people with type 2 diabetes: a randomised, double-blind, placebo and active-controlled, parallel-group, phase 2 trial PMID: 37385280 Lancet

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Serious adverse effects have not been widely reported, but long-term safety data in humans is lacking

Based on these assessments, studies were categorized as having low, moderate, or high risk of bias allowing methodological quality to be transparently considered during interpretation of the findings