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During tumorigenesis, abnormal hypermethylation of the cytosine in CpG islands and hypomethylation of the whole genome result in genome instability and alterations in gene expression profile, including silencing of tumor suppressor genes, endogenous retro-elements, and tumor antigens, and activation of oncogenes (Liang and Weisenberger, 2017
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RTs Three Key Takeaways: Strong Response Subtype : Research presented at the 2026 ATS International Conference identified a subgroup of patients who experienced nearly twice the improvement in sleep apnea severity compared to other participants
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