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The market movements were caused by the positive results on the phase 2 drug candidate LY3298176

However, treatment with L-Ca in a dose dependent manner significantly reduced KIM-1 and NGAL gene expression

Glucagon Thermogenesis GLP Diabetes Care 2023 View on PubMed GIP Receptor Agonism: Beyond Insulin Secretion to Adipose Tissue Remodeling Finding: GIP receptor (GIPR) activation was found to have direct effects on adipose tissue: improved fat storage efficiency (reduced ectopic fat), enhanced insulin sensitivity in adipocytes, and modulation of adipokine secretion (increased adiponectin, reduced resistin)

This is one reason supervised programs and resistance training are even more important as you get leaner