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Aksoy S, Szumlanski CL, Weinshilboum RM
Mechanisms of Tirzepatide: GLP-1 receptors GIP receptors This dual action produces powerful effects on appetite regulation, insulin sensitivity, blood sugar control, and energy balance
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It uses a methyl group donated by S-adenosylmethionine (SAM) to methylate nicotinamide a vitamin B3 form that would otherwise be recycled back into NAD+
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