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The general reaction involves formation of an unsymmetrical disulfide from the protectable protein (RSH) and GSH: [24] RSH + GSH + [O] GSSR + H 2 O Glutathione is also employed for the detoxification of methylglyoxal and formaldehyde, toxic metabolites produced under oxidative stress
The stomach acid can break down the glutathione before it reaches the bloodstream, which is why many people do not experience significant benefits from oral consumption
When administered by trained medical professionals, glutathione IV therapy is generally considered safe for healthy adults
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